Cyanocobalamin
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 5g | $500 | Check With Us |
| 10g | $750 | Check With Us |
| 20g | $1125 | Check With Us |
: Cat #: V18434 CAS #: 68-19-9 Purity ≥ 99%
Description: Cyanocobalamin is a novel and potent cobalt coordination compound.
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| Molecular Weight (MW) | 1355.37 |
|---|---|
| Molecular Formula | C63H88CoN14O14P |
| CAS No. | 68-19-9 |
| SMILES Code | Cc(c(C)c1)cc2c1[n+]3cn2C4C(C(C(O4)CO)OP(OC(CNC(CCC5(C(C6C7(C(CC(N)=O)(C(C8=N7[Co+3]39%10([N-]6C5=C(C%11=N9C(C(C)(C%11CCC(N)=O)C)=CC%12=N%10C(C(CC(N)=O)(C%12CCC(N)=O)C)=C8C)C)[CH-]#N)CCC(N)=O)C)C)CC(N)=O)C)=O)C)([O-])=O)O |
| Synonyms | Cyanocobalamin; Vitamin B12; Docigram; NSC 80365; NSC-80365; NSC80365; |
| Protocol | In Vitro | Vitamin B12 is one of the eight B vitamins. It is normally involved in the metabolism of every cell of the human body, especially affecting DNA synthesis and regulation, but also fatty acid synthesis (especially odd chain fatty acids) and energy production. However, many (though not all) of the effects of functions of B12 can be replaced by sufficient quantities of folic acid (vitamin B9), since B12 is used to regenerate folate in the body. Most vitamin B12 deficiency symptoms are actually folate deficiency symptoms, since they include all the effects of pernicious anemia and megaloblastosis, which are due to poor synthesis of DNA when the body does not have a proper supply of folic acid for the production of thymine due to methyl trapping. When sufficient folic acid is available, all known B12 related deficiency syndromes normalize, save those narrowly connected with the vitamin B12-dependent enzymes Methylmalonyl Coenzyme A mutase, and 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR), also known as methionine synthase; and the buildup of their respective substrates (methylmalonic acid, MMA) and homocysteine.Coenzyme B12's reactive C-Co bond participates in three main types of enzyme-catalyzed reactions. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 0.7378 mL | 3.6890 mL | 7.3781 mL | 14.7561 mL |
| 5mM | 0.1476 mL | 0.7378 mL | 1.4756 mL | 2.9512 mL |
| 10mM | 0.0738 mL | 0.3689 mL | 0.7378 mL | 1.4756 mL |
| 20mM | 0.0369 mL | 0.1845 mL | 0.3689 mL | 0.7378 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.