CVT-12012
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
100mg | $650 | To Be Confirmed |
250mg | $1300 | To Be Confirmed |
500mg | $1950 | To Be Confirmed |
Cat #: V2687 CAS #: 1018675-35-8 Purity ≥ 98%
Description: CVT-12012 (also known as CVT12012, CVT 12012) is an orally bioavailable stearoyl-coA desaturase (SCD) inhibitor (IC50s = 38 nM, 6.1 nM for rat microsomal and human HEPG2).
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
Molecular Weight (MW) | 434.41 |
---|---|
Molecular Formula | C21H21F3N4O |
CAS No. | 1018675-35-8 |
Storage | -20℃ for 3 years in powder formr |
-80℃ for 2 years in solvent | |
Solubility In Vitro | DMSO: 10 mMr |
Water: N/Ar | |
Ethanol: N/A | |
SMILES Code | O=C(NCCN1C(C(C)=NC2=C1C=C(NCC3=CC=CC(C(F)(F)F)=C3)C=C2)=O)CO |
Synonyms | UNII-OH3J29Q653; CVT-12012; CVT 12012; CVT12012 |
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 2.3020 mL | 11.5099 mL | 23.0197 mL | 46.0395 mL |
5mM | 0.4604 mL | 2.3020 mL | 4.6039 mL | 9.2079 mL |
10mM | 0.2302 mL | 1.1510 mL | 2.3020 mL | 4.6039 mL |
20mM | 0.1151 mL | 0.5755 mL | 1.1510 mL | 2.3020 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.