Corydaline
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
50mg | $600 | Check With Us |
100mg | $950 | Check With Us |
200mg | $1500 | Check With Us |
Cat #: V11209 CAS #: 518-69-4 Purity ≥ 98%
Description: Corydaline is a bioactive and naturally occurring isoquinoline alkaloid extracted from Corydalis yanhusuo.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
Molecular Weight (MW) | 369.45 |
---|---|
Molecular Formula | C22H27NO4 |
CAS No. | 518-69-4 |
Protocol | In Vitro | Corydaline (12.5-50 µM; 24 hours) treatment inhibits EV71 replication by suppressing the COX-2 expression and the phosphorylation of JNK MAPK and P38 MAPK but not ERK MAPK in vitro |
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In Vivo | Corydaline (10 mg/kg; subcutaneous administration; once) treatment shows antinociceptive effects in mice by significantly inhibiting the writhing behavior | |
Animal model | Male CD1 mice (30-35 g, 7-8 weeks old) injected with acetic acid | |
Dosages | 10 mg/kg | |
Administration | Subcutaneous administration; once |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 2.7067 mL | 13.5336 mL | 27.0673 mL | 54.1345 mL |
5mM | 0.5413 mL | 2.7067 mL | 5.4135 mL | 10.8269 mL |
10mM | 0.2707 mL | 1.3534 mL | 2.7067 mL | 5.4135 mL |
20mM | 0.1353 mL | 0.6767 mL | 1.3534 mL | 2.7067 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.