Cortistatin-14 TFA

This product is for research use only, not for human use. We do not sell to patients.

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Cat #: V32102 CAS #: 186901-48-4 Purity ≥ 99%

Description: Cortistatin-14 TFA (CST-14) is a novel and potent cyclic neuropeptide that has structural similarity to somatostatin-14. Cortistatin-14 exerts anticonvulsive, neuroprotective effect and anti-inflammatory activity by binding to the somatostatin receptors (sst1-sst5). Cortistatin (CST-14) is a recently discovered endogenous peptide which shares similarity to somatostatin and binds to somatostatin receptors.

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Molecular Weight (MW)	1720.03
Molecular Formula	C₈₁H₁₁₄N₂₀O₁₈S₂
CAS No.	186901-48-4

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	0.5814 mL	2.9069 mL	5.8139 mL	11.6277 mL
5mM	0.1163 mL	0.5814 mL	1.1628 mL	2.3255 mL
10mM	0.0581 mL	0.2907 mL	0.5814 mL	1.1628 mL
20mM	0.0291 mL	0.1453 mL	0.2907 mL	0.5814 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.