Clioquinol

This product is for research use only, not for human use. We do not sell to patients.

Clioquinol
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100g$400Check With Us
200g$550Check With Us
500mg$925Check With Us

Cat #: V18488 CAS #: 130-26-7 Purity ≥ 99%

Description: Clioquinol (Iodochlorhydroxyquin) is a neurotoxic antibiotic, an antifungal drug and antiprotozoal agent that is effective against Alzheimer's disease/AD and can induce cancer cell death.

References: Moe Wehbe, et al. Development of a copper-clioquinol formulation suitable for intravenous use. Drug Deliv Transl Res. 2018 Feb;8(1):239-251.

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Molecular Weight (MW)305.50
Molecular FormulaC9H5ClINO
CAS No.130-26-7
SMILES CodeOC1=C2N=CC=CC2=C(Cl)C=C1I
SynonymsEnteroVioform, Clioquinol, Chinoform, Vioform, Iodochlorhydroxyquin, Entero Septol
ProtocolIn VitroClioquinol (0.01-1000 uM; 72 hours) shows anticancer activity against U251, and MV-4-11 cells.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.2733 mL16.3666 mL32.7332 mL65.4664 mL
5mM0.6547 mL3.2733 mL6.5466 mL13.0933 mL
10mM0.3273 mL1.6367 mL3.2733 mL6.5466 mL
20mM0.1637 mL0.8183 mL1.6367 mL3.2733 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.