Clevidipine Butyrate

This product is for research use only, not for human use. We do not sell to patients.

Clevidipine Butyrate
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$650Check With Us
1g$1050Check With Us
5g$2835Check With Us

Cat #: V0610 CAS #: 167221-71-8 Purity ≥ 98%

Description: Clevidipine (Cleviprex) is a potent and short acting, dihydropyridine-based L-type calcium channel blocker used for reducing blood pressure when oral therapy is not feasible or not desirable.

References: Yi X, Vivien B, Lynch C 3rd. Clevidipine blockade of L-type Ca2+ currents: steady-state and kinetic electrophysiological studies in guinea pigventricular myocytes.

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Product Promise

Promise
Molecular Weight (MW)456.32
Molecular FormulaC21H23Cl2NO6
CAS No.167221-71-8
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 91 mg/mL (199.4 mM)r
Water: < 1 mg/mLr
Ethanol: 3 mg/mL (6.6 mM)
SynonymsClevidipine; Clevidipine butyrate; Cleviprex; Clevelox; Rac-Clevidipine
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.1914 mL10.9572 mL21.9144 mL43.8289 mL
5mM0.4383 mL2.1914 mL4.3829 mL8.7658 mL
10mM0.2191 mL1.0957 mL2.1914 mL4.3829 mL
20mM0.1096 mL0.5479 mL1.0957 mL2.1914 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.