Clascoterone
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 1g | $845 | Check With Us |
| 2g | $1345 | Check With Us |
| 5g | $2100 | Check With Us |
: Cat #: V13466 CAS #: 19608-29-8 Purity ≥ 99%
Description: Clascoterone (cortexolone 17alpha-propionate; CB-03-01; Winlevi; Breezula) is a novel and potent androgen antagonist that has been approved in 2020 for topical use in the treatment of acne.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 402.53 |
|---|---|
| Molecular Formula | C24H34O5 |
| CAS No. | 19608-29-8 |
| Synonyms | CB03-01; CB 03-01 |
| Protocol | In Vivo | Clascoterone is a new potent topical antiandrogen potentially useful in acne vulgaris. Clascoterone 1% cream was very well tolerated, and was significantly better than placebo regarding TLC (P = 0·0017), ILC (P = 0·0134) and ASI (P = 0·0090), and also clinically more effective than comparator. The product also induced a faster attainment of 50% improvement in all the above parameters. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.4843 mL | 12.4214 mL | 24.8429 mL | 49.6857 mL |
| 5mM | 0.4969 mL | 2.4843 mL | 4.9686 mL | 9.9371 mL |
| 10mM | 0.2484 mL | 1.2421 mL | 2.4843 mL | 4.9686 mL |
| 20mM | 0.1242 mL | 0.6211 mL | 1.2421 mL | 2.4843 mL |
The molarity calculator equation
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The dilution calculator equation
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This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.