Cinepazide maleate (MD-67350)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
1g	$420	Check With Us
2g	$650	Check With Us
5g	$1050	Check With Us

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Cat #: V1258 CAS #: 26328-04-1 Purity ≥ 98%

Description: Cinepazide maleate (NSC291562; MD-67350; MD67350; Brendil; Vasodistal; Kelinao or Anjieli), the maleate salt form of cinepazide,is a vasodilator used in China for the treatment of cardiovascular, cerebrovascular, and peripheral vascular diseases.

References: Akashi, A., et al., [Cardiovascular pharmacology of cinepazide, a new cerebral vasodilator (author's transl)]. Nihon Yakurigaku Zasshi, 1979. 75(5): p. 507-16.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	533.57
Molecular Formula	C22H31N3O5.C4H4O4
CAS No.	26328-04-1
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 107 mg/mL (200.5 mM)r
	Water: 107 mg/mL (200.5 mM)r
	Ethanol: <1 mg/mL
Synonyms	NSC-291562; Cinepazide maleate; Cinepazide; MD 67350; NSC 291562; NSC291562; MD-67350; MD67350; Brendil; Vasodistal

Protocol	In Vivo	Cinepazide Maleate (intravenous injection; 30 mg/kg) potentiates the vertebral vasodilator response of dogs to intravertebral adenosine and cyclic AMP, while cinnarizine reduces their vasodilator effects

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.8742 mL	9.3708 mL	18.7417 mL	37.4834 mL
5mM	0.3748 mL	1.8742 mL	3.7483 mL	7.4967 mL
10mM	0.1874 mL	0.9371 mL	1.8742 mL	3.7483 mL
20mM	0.0937 mL	0.4685 mL	0.9371 mL	1.8742 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.