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Cilazapril Monohydrate (Ro 31-2848)

This product is for research use only, not for human use. We do not sell to patients.

Cilazapril Monohydrate (Ro 31-2848)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$620Check With Us
500mg$990Check With Us
1g$1485Check With Us
email: [email protected]        [email protected]

Cat #: V1794 CAS #: 92077-78-6 Purity ≥ 98%

Description: Cilazapril Monohydrate (Ro 31-2848) is a potent angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.

References: Szucs, T., Cilazapril. A review. Drugs, 1991. 41 Suppl 1: p. 18-24.

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Molecular Weight (MW)435.51
Molecular FormulaC22H31N3O5.H2O
CAS No.92077-78-6
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 87 mg/mL (199.8 mM)r
Water: <1 mg/mLr
Ethanol: 87 mg/mL (199.8 mM)
SynonymsRo 31-2848 monohydrate; Ro31-2848 monohydrate; Ro-31-2848 monohydrate; Ro-31 2848 monohydrate;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.2962 mL11.4808 mL22.9616 mL45.9232 mL
5mM0.4592 mL2.2962 mL4.5923 mL9.1846 mL
10mM0.2296 mL1.1481 mL2.2962 mL4.5923 mL
20mM0.1148 mL0.5740 mL1.1481 mL2.2962 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
=
Concentration
 
×
Volume
 
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
×
 
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.