CID1375606
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $950 | Check With Us |
| 500mg | $1550 | Check With Us |
| 1g | $2325 | Check With Us |
: Cat #: V3995 CAS #: 313493-80-0 Purity ≥ 98%
Description: CID 1375606 is the first selective surrogate agonist of orphan G protein-coupled receptor (GPCR) GPR27 identified from screening a diversity-oriented synthesis library.
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- Physicochemical and Storage Information
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| Molecular Weight (MW) | 385.24 |
|---|---|
| Molecular Formula | C20H14Cl2N2O2 |
| CAS No. | 313493-80-0 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: ≥ 50mg/mLr |
| Water: N/Ar | |
| Ethanol: N/A | |
| SMILES Code | O=C(N(C1=CC=CC=C1)C(NC2=CC=CC=C2)=O)C3=CC=C(Cl)C=C3Cl |
| Synonyms | CID 1375606; CID1375606; CID-1375606 |
| Protocol | In Vitro | CID 1375606 is a GPR27-specific surrogate agonist. GPR27 is characterized by a high level of conservation among vertebrates and a predominant expression in the central nervous system. In addition, it has recently been linked to insulin secretion |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.5958 mL | 12.9789 mL | 25.9578 mL | 51.9157 mL |
| 5mM | 0.5192 mL | 2.5958 mL | 5.1916 mL | 10.3831 mL |
| 10mM | 0.2596 mL | 1.2979 mL | 2.5958 mL | 5.1916 mL |
| 20mM | 0.1298 mL | 0.6489 mL | 1.2979 mL | 2.5958 mL |
The molarity calculator equation
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The dilution calculator equation
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This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.