CID-5951923
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $1725 | To Be Confirmed |
| 200mg | $2585 | To Be Confirmed |
| 500mg | $4360 | To Be Confirmed |
: Cat #: V18316 CAS #: 749872-43-3 Purity ≥ 99%
Description: CID-5951923 (CID5951923) is a novel and potent inhibitor of Kruppel-like factor 5 (KLF5) expression (IC50 of 603 nM) with anticancer activity.
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| Molecular Weight (MW) | 382.39 |
|---|---|
| Molecular Formula | C16H18N2O7S |
| CAS No. | 749872-43-3 |
| SMILES Code | O=C(OCC(N(C(CC1)CS1(=O)=O)C)=O)/C=C/C2=CC=CC([N+]([O-])=O)=C2 |
| Synonyms | CID-5951923; CID 5951923; CID5951923; |
| Protocol | In Vitro | CID 5951923 (10 μM) inhibits proliferation of cancer cell lines mainly in highly express KLF5 cells. CID 5951923 (10 μM; 24 h) significantly decreases endogenous KLF5 levels in the DLD-1 cells, increases phosphorylation levels of pEGFFpY1068, and downregulated EGR1. CID 5951923 (1 nM-100 μM; 48 h) inhibits proliferation of DLD-1 cells in a dose-dependent manner. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.6151 mL | 13.0757 mL | 26.1513 mL | 52.3026 mL |
| 5mM | 0.5230 mL | 2.6151 mL | 5.2303 mL | 10.4605 mL |
| 10mM | 0.2615 mL | 1.3076 mL | 2.6151 mL | 5.2303 mL |
| 20mM | 0.1308 mL | 0.6538 mL | 1.3076 mL | 2.6151 mL |
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Step One: Enter information below
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Step Two: Enter the in vivo formulation
%DMSO
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%ddH2O
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Method for preparing DMSO master liquid:
mg
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,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.