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CID-25014542

This product is for research use only, not for human use. We do not sell to patients.

CID-25014542
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Size Price Stock
250mg$1680Check With Us
500mg$2520Check With Us
1g$3780Check With Us

Cat #: V6701 CAS #: 220904-99-4 Purity ≥ 99%

Description: CID-25014542 is novel and potent inhibitor of Raf kinases with potential antineoplastic activity.

References: German, et al. Benzylidene-1,3-dihydro-indol-2-one derivatives as receptor tyrosine kinase inhibitors, particularly of raf kinases. patent/EP1003721B1

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Molecular Weight (MW)429.49
Molecular FormulaC15H8Br2ClNO2
CAS No.220904-99-4
SMILES CodeO=C1NC2=C(C=C(Cl)C=C2)/C1=C/C3=CC(Br)=C(O)C(Br)=C3 
SynonymsCID-25014542; CID25014542; CID 25014542
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.3283 mL11.6417 mL23.2834 mL46.5669 mL
5mM0.4657 mL2.3283 mL4.6567 mL9.3134 mL
10mM0.2328 mL1.1642 mL2.3283 mL4.6567 mL
20mM0.1164 mL0.5821 mL1.1642 mL2.3283 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.