CHMFL-ABL-121

This product is for research use only, not for human use. We do not sell to patients.

CHMFL-ABL-121
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1mg$200To Be Confirmed
email: sales@invivochem.com        sales@invivochem.cn

Cat #: V31396 CAS #: 2270879-07-5 Purity ≥ 99%

Description: CHMFL-ABL-121 (CHMFL-ABL121) is a novel and potent ABL kinase inhibitor (IC50s = 2 nM and 0.2 nM for purified inactive ABL wt and T315I kinase protein) with anticancer activity.

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Molecular Weight (MW)580.67
Molecular FormulaC30H31F3N6OS
CAS No.2270879-07-5
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.7221 mL8.6107 mL17.2215 mL34.4430 mL
5mM0.3444 mL1.7221 mL3.4443 mL6.8886 mL
10mM0.1722 mL0.8611 mL1.7221 mL3.4443 mL
20mM0.0861 mL0.4305 mL0.8611 mL1.7221 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
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Volume(start)
V1
 
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Concentration(final)
C2
 
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.