cFMS Receptor Inhibitor II
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
100mg | $1950 | Check With Us |
250mg | $3250 | Check With Us |
500mg | $4875 | Check With Us |
Cat #: V4438 CAS #: 959860-85-6 Purity ≥ 98%
Description: cFMS Receptor Inhibitor II (BUN60856; BUN-60856) is a novel, cell-permeable and potent CSF1R (Colony stimulating factor 1 receptor) kinase inhibitor with an IC50 of 80 nM.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
Molecular Weight (MW) | 368.43 |
---|---|
Molecular Formula | C₂₃H₂₀N₄O |
CAS No. | 959860-85-6 |
Storage | -20℃ for 3 years in powder formr |
-80℃ for 2 years in solvent | |
SMILES Code | O=C(C1=C(NC2=CC=C(C)C(C)=C2)C3=CC=C(C4=CC=NC=C4)C=C3N=C1)N |
Synonyms | cFMS Receptor Inhibitor II; cFMS Receptor Inhibitor-II; BUN60856; BUN-60856; BUN 60856 |
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 2.7142 mL | 13.5711 mL | 27.1422 mL | 54.2844 mL |
5mM | 0.5428 mL | 2.7142 mL | 5.4284 mL | 10.8569 mL |
10mM | 0.2714 mL | 1.3571 mL | 2.7142 mL | 5.4284 mL |
20mM | 0.1357 mL | 0.6786 mL | 1.3571 mL | 2.7142 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.