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Cerestat (Aptiganel; CNS 1102) HCl

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Cerestat (Aptiganel; CNS 1102) HCl
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Cat #: V41654 CAS #: 137160-11-3 Purity ≥ 99%

Description: Cerestat (Aptiganel; CNS-1102) HCl, noncompetitive NMDA antagonist with neuroprotective effects and has the potential to be used for the treatment of stroke.

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Molecular Weight (MW)339.87
Molecular FormulaC20H22ClN3
CAS No.137160-11-3
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.9423 mL14.7115 mL29.4230 mL58.8460 mL
5mM0.5885 mL2.9423 mL5.8846 mL11.7692 mL
10mM0.2942 mL1.4712 mL2.9423 mL5.8846 mL
20mM0.1471 mL0.7356 mL1.4712 mL2.9423 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.