Cefuroxime Sodium

This product is for research use only, not for human use. We do not sell to patients.

Cefuroxime Sodium
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
25g$450Check With Us
50g$675Check With Us
100g$1010Check With Us

Cat #: V10936 CAS #: 56238-63-2 Purity ≥ 99%

Description: Cefuroxime Sodium (Zinacef) is a 2nd-generation cephalosporin antibiotic used to treat and prevent a number of bacterial infections including pneumonia, meningitis, otitis media, sepsis, urinary tract infections, and Lyme disease.

References: D M Ryan, et al. Cefuroxime sodium, a New Cephalosporin Antibiotic: Activity in Vivo. Antimicrob Agents Chemother. 1976 Mar;9(3):520-5.

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Product Promise

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Molecular Weight (MW)446.37
Molecular FormulaC16H15N4NaO8S
CAS No.56238-63-2
ProtocolIn VivoRabbits (weighing 2.0 to 2.5 kg) are challenged intravenously with S. aureus strain 630 (a penicillinase-producing strain), the median effective dose of Cefuroxime sodium is 3 mg/kg as a result of the protection test
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.2403 mL11.2015 mL22.4029 mL44.8059 mL
5mM0.4481 mL2.2403 mL4.4806 mL8.9612 mL
10mM0.2240 mL1.1201 mL2.2403 mL4.4806 mL
20mM0.1120 mL0.5601 mL1.1201 mL2.2403 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.