Cefotaxime Sodium

This product is for research use only, not for human use. We do not sell to patients.

Cefotaxime Sodium
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1g$180Check With Us
5g$300Check With Us
10g$450Check With Us

Cat #: V17844 CAS #: 64485-93-4 Purity ≥ 99%

Description: Cefotaxime Sodium is a novel and potent Cephalosporin antibiotic agent.

References: Woodfield JC, et al. A comparison of the prophylactic efficacy of ceftriaxone and cefotaxime in abdominal surgery. Am J Surg. 2003 Jan;185(1):45-9.

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Molecular Weight (MW)477.45
Molecular FormulaC16H16N5NaO7S2
CAS No.64485-93-4
SMILES CodeCC(=O)OCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N\OC)/C3=CSC(=N3)N)SC1)C(=O)[O-].[Na+]
SynonymsCefotaxime Sodium; CEFOTAXIME SODIUM SALT; Cefotaxim sodium salt; Cefotax; CHEBI:3498; Merck Brand of Cefotaxime Sodium; Pisa Brand of Cefotaxime Sodium; Primafen; Ru 24756; Ru-24756; Ru24756; Sodium, Cefotaxime; Taporin; Viken Brand of Cefotaxime Sodium;
ProtocolIn VitroCefotaxime sodium exhibits an MIC of 0.0625 mg/L for V. vulnificus CMCP6.
In VivoThe combination of ciprofloxacin and cefotaxime is more effective in clearing V. vulnificus in vivo than previously used regimens.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.0945 mL10.4723 mL20.9446 mL41.8892 mL
5mM0.4189 mL2.0945 mL4.1889 mL8.3778 mL
10mM0.2094 mL1.0472 mL2.0945 mL4.1889 mL
20mM0.1047 mL0.5236 mL1.0472 mL2.0945 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.