Cefazolin Sodium (cefazoline; cephazolin)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 10g | $450 | Check With Us |
| 25g | $750 | Check With Us |
| 50g | $1125 | Check With Us |
: Cat #: V11838 CAS #: 27164-46-1 Purity ≥ 98%
Description: Cefazolin sodium (cefazoline and cephazolin) is a 1st generation beta-lactam class of antibiotic used for the treatment of a number of bacterial infections.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 476.49 |
|---|---|
| Molecular Formula | C14H13N8NaO4S3 |
| CAS No. | 27164-46-1 |
| SMILES Code | CC1=NN=C(S1)SCC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)CN4C=NN=N4)SC2)C(=O)[O-].[Na+] |
| Synonyms | monosodium cephazolin; Cefazolin sodium salt; Sodium cefazolin; Sodium cephazolin; Kefzol; Sodium Cephazolin; Sodium, Cefazolin; Sodium, Cephazolin; Totacef |
| Protocol | In Vitro | Cefazolin sodium (0-300 μg/ml; 6 or 24 h) has a direct anti-inflammatory effect on C8-B4 cells stimulated by lipopolysaccharide |
|---|---|---|
| In Vivo | Cefazolin sodium (Subcutaneous injection; 300-500 mg/kg; once daily; 5 d) treatment improves learning and memory in mice after surgery | |
| Animal model | 6- to 8-week-old male CD-1 mice underwent clinical exploratory laparotomy | |
| Dosages | 300-500 mg/kg | |
| Administration | Subcutaneous injection; 300-500 mg/kg; once daily; 5 days |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.0987 mL | 10.4934 mL | 20.9868 mL | 41.9736 mL |
| 5mM | 0.4197 mL | 2.0987 mL | 4.1974 mL | 8.3947 mL |
| 10mM | 0.2099 mL | 1.0493 mL | 2.0987 mL | 4.1974 mL |
| 20mM | 0.1049 mL | 0.5247 mL | 1.0493 mL | 2.0987 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.