Cedirogant
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $3250 | Check With Us |
| 200mg | $4875 | Check With Us |
| 500mg | $8225 | Check With Us |
: Cat #: V3130 CAS #: 2055496-11-0 Purity ≥ 99%
Description: Cedirogant (also known as ABBV-157) is a novel and orally active RORγt inverse agonist.
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 547.78 |
|---|---|
| Molecular Formula | C24H20Cl3F3N2O3 |
| CAS No. | 2055496-11-0 |
| SMILES Code | O=C(O)CC1CCN(C(C2=CC=C(Cl)C(CN3C=CC4=C3C(Cl)=CC(C(F)(F)F)=C4)=C2Cl)=O)CC1 |
| Synonyms | Cedirogant ,ABBV-157; ABBV157; ABBV 157 |
| Protocol | In Vitro | The transcription factor retinoic acid-related orphan receptor gamma t (RORγt) has been identified as the master regulator of TH17 cell differentiation and IL-17/22 production and is therefore an attractive target for the treatment of inflammatory diseases. Cedirogant (ABBV-157) has the potential for chronic plaque psoriasis research. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.8256 mL | 9.1278 mL | 18.2555 mL | 36.5110 mL |
| 5mM | 0.3651 mL | 1.8256 mL | 3.6511 mL | 7.3022 mL |
| 10mM | 0.1826 mL | 0.9128 mL | 1.8256 mL | 3.6511 mL |
| 20mM | 0.0913 mL | 0.4564 mL | 0.9128 mL | 1.8256 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.