CE-245677

This product is for research use only, not for human use. We do not sell to patients.

CE-245677
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5mg$140To Be Confirmed
10mg$230To Be Confirmed
50mg$500To Be Confirmed
100mg$770To Be Confirmed
email: sales@invivochem.com        sales@invivochem.cn

Cat #: V17791 CAS #: 717899-97-3 Purity ≥ 99%

Description: CE-245677 is a potent, reversible inhibitor of Tie2 and TrkA/B with IC50s of 4.7 and 1 nM respectively in cell systems.

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Molecular Weight (MW)513.3759
Molecular FormulaC24H22CL2N6O3
CAS No.717899-97-3
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

SynonymsCE245677; CE 245677; CE-245677
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.9479 mL9.7395 mL19.4789 mL38.9578 mL
5mM0.3896 mL1.9479 mL3.8958 mL7.7916 mL
10mM0.1948 mL0.9739 mL1.9479 mL3.8958 mL
20mM0.0974 mL0.4870 mL0.9739 mL1.9479 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
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Volume(start)
V1
 
=
 
Concentration(final)
C2
 
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Volume(final)
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.