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CCR2 antagonist 4 HCl

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CCR2 antagonist 4 HCl
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
10mg$1503-6 Days
25mg$2503-6 Days
50mg$4503-6 Days
100mg$7503-6 Days

Cat #: V39099 CAS #: 1313730-14-1 Purity ≥ 99%

Description: CCR2 antagonist 4 HCl (Teijin compound 1 hydrochloride) is a novel and potent CCR2 antagonist (IC50=180 nM for CCR2b) with anti-inflammatory and immunomodulatory effects.

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Molecular Weight (MW)476.32
Molecular FormulaC₂₁H₂₂Cl₂F₃N₃O₂
CAS No.1313730-14-1
SynonymsCCR2 antagonist 4 HCl
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.0994 mL10.4971 mL20.9943 mL41.9886 mL
5mM0.4199 mL2.0994 mL4.1989 mL8.3977 mL
10mM0.2099 mL1.0497 mL2.0994 mL4.1989 mL
20mM0.1050 mL0.5249 mL1.0497 mL2.0994 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.