Candesartan D4 (CV-11974 D4)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
25mg	$2250	To Be Confirmed
50mg	$3375	To Be Confirmed
100mg	$5060	To Be Confirmed

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Cat #: V33156 CAS #: 1346604-70-3 Purity ≥ 99%

Description: Candesartan D4 (CV-11974 D4) is the tetra-deuterated form (in the central phenyl ring) of form of Candesartan (formerly TCV-116; CV-11974; Atacand), which is an angiotensin II receptor antagonist (AT II inhibitor) approved for treating hypertension and congestive heart failure.

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Molecular Weight (MW)	444.48
Molecular Formula	C24H16D4N6O3
CAS No.	1346604-70-3

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.2498 mL	11.2491 mL	22.4982 mL	44.9964 mL
5mM	0.4500 mL	2.2498 mL	4.4996 mL	8.9993 mL
10mM	0.2250 mL	1.1249 mL	2.2498 mL	4.4996 mL
20mM	0.1125 mL	0.5625 mL	1.1249 mL	2.2498 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.