Canagliflozin D4

This product is for research use only, not for human use. We do not sell to patients.

Canagliflozin D4
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
20mg$2175To Be Confirmed
50mg$3330To Be Confirmed
100mg$4995To Be Confirmed

Cat #: V40443 CAS #: 1997338-61-0 Purity ≥ 99%

Description: Canagliflozin D4 is the tetra-deuterated form of Canagliflozin (TA-7284; JNJ-24831754ZAE; JNJ 28431754-AAA; JNJ-28431754; Invokana) which is a selective SGLT2 inhibitor approved by FDA for the treatment of type 2 diabetes.

References: Liang Y, et al. Effect of canagliflozin on renal threshold for glucose, glycemia, and body weight in normal and diabetic animal models. PLoS One. 2012;7(2):e30555.

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Molecular Weight (MW)448.54
Molecular FormulaC₂₄H₂₁D₄FO₅S
CAS No.1997338-61-0
SynonymsCanagliflozin D4
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.2295 mL11.1473 mL22.2946 mL44.5891 mL
5mM0.4459 mL2.2295 mL4.4589 mL8.9178 mL
10mM0.2229 mL1.1147 mL2.2295 mL4.4589 mL
20mM0.1115 mL0.5574 mL1.1147 mL2.2295 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.