Burixafor HBr

This product is for research use only, not for human use. We do not sell to patients.

Burixafor HBr
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1160To Be Confirmed
500mg$1650To Be Confirmed
1g$2475To Be Confirmed

Cat #: V5009 CAS #: 1191450-19-7 (HBr) Purity ≥ 98%

Description: Burixafor HBr, the hydrobromide salt of Burixafor (TG-0054), is a novel, potent and orally bioavailable antagonist of CXCR4 (CXC chemokine receptor 4) with potential anti-inflammatory activity.

References: Shelke NB, et al. Intravitreal Poly(L-lactide) Microparticles Sustain Retinal and Choroidal Delivery of TG-0054, a Hydrophilic Drug Intended for Neovascular Diseases. Drug Deliv Transl Res. 2011 Feb;1(1):76-90.

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Product Promise

Promise
Molecular Weight (MW)769.01
Molecular FormulaC27H51N8O3P
CAS No.1191450-19-7 (HBr)
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.3004 mL6.5019 mL13.0037 mL26.0075 mL
5mM0.2601 mL1.3004 mL2.6007 mL5.2015 mL
10mM0.1300 mL0.6502 mL1.3004 mL2.6007 mL
20mM0.0650 mL0.3251 mL0.6502 mL1.3004 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.