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BTS

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BTS
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Size Price Stock
10g$180Check With Us
25g$320Check With Us
50g$480Check With Us
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Cat #: V17176 CAS #: 1576-37-0 Purity ≥ 98%

Description: BTS is a novel and potent inhibitor of ATPase activity of skeletal muscle myosin II subfragment 1 (S1), specifically the Ca2+-stimulated myosin S1 ATPase (IC50 = 5 μM).

References: Cheung A, et al. A small-molecule inhibitor of skeletal muscle myosin II. Nat Cell Biol. 2002 Jan;4(1):83-8.

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Molecular Weight (MW)261.33
Molecular FormulaC14H15NO2S
CAS No.1576-37-0
SynonymsBnNHTs
ProtocolIn VitroBTS (2-12 μM) inhibits the Ca2+-stimulated ATPase activity of myosin S1 in the absence of actin, with an IC50 of ~5 µM
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.8266 mL19.1329 mL38.2658 mL76.5316 mL
5mM0.7653 mL3.8266 mL7.6532 mL15.3063 mL
10mM0.3827 mL1.9133 mL3.8266 mL7.6532 mL
20mM0.1913 mL0.9566 mL1.9133 mL3.8266 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
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Volume(start)
V1
 
=
 
Concentration(final)
C2
 
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.