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| Size | Price | Stock |
|---|---|---|
| 5mg | $250 | 3-6 Days |
| 10mg | $450 | 3-6 Days |
| 25mg | $750 | 3-6 Days |
| 50mg | $1250 | 3-6 Days |
| 100mg | $1950 | 3-6 Days |
: Cat #: V17165 CAS #: 1257423-87-2 Purity ≥ 99%
Description: BTdCPU is an activator of HRI (heme-regulated eIF2α kinase) with anticancer activity. It can promote eIF2α phosphorylation and induced apoptosis in resistant cells. The eIF2-alpha kinase HRI is a novel therapeutic target in multiple myeloma. Combination therapy with rapamycin, an mTOR inhibitor, and BTdCPU, an activator of HRI, demonstrated additive effects on apoptosis in dex-resistant cells. Thus, specific activation of the eIF2α kinase HRI is a novel therapeutic target in MM that can augment current treatment strategies.
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| CAS No. | 1257423-87-2 |
|---|
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.