Bruceine A (Dihydrobrusatol; NSC310616)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
100mg	$1150	To Be Confirmed
250mg	$1800	To Be Confirmed
500mg	$2700	To Be Confirmed

: [email protected] [email protected]

Cat #: V5099 CAS #: 25514-31-2 Purity ≥ 98%

Description: Bruceine A (NSC310616 and Dihydrobrusatol) is a naturally occuring quassinoid compound isolated from the dried fruits of Brucea javanica (L.); it has the potential for the treatment of canine babesiosis.

References: Nakao R, et al. Evaluation of efficacy of bruceine A, a natural quassinoid compound extracted from a medicinal plant, Brucea javanica, for canine babesiosis. J Vet Med Sci. 2009 Jan;71(1):33-41.

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Physicochemical and Storage Information
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Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	522.54
Molecular Formula	C₂₆H₃₄O₁₁
CAS No.	25514-31-2
Storage	-20℃ for 3 years in powder formrr
Storage	-80℃ for 2 years in solvent
SMILES Code	O=C([C@@]1([C@H]([C@H](O)[C@]2([H])[C@]3(C4)C)O)[C@@]([C@H](C5=O)OC(CC(C)C)=O)([H])[C@@]2([C@@](O5)([H])C[C@@]3([H])C(C)=C(O)C4=O)CO1)OC
Synonyms	NSC310616; NSC 310616; NSC-310616; Dihydrobrusatol;

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.9137 mL	9.5686 mL	19.1373 mL	38.2746 mL
5mM	0.3827 mL	1.9137 mL	3.8275 mL	7.6549 mL
10mM	0.1914 mL	0.9569 mL	1.9137 mL	3.8275 mL
20mM	0.0957 mL	0.4784 mL	0.9569 mL	1.9137 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.