Broxaldine (Brobenzoxaldine)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
250mg	$420	Check With Us
500mg	$630	Check With Us
1g	$945	Check With Us

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Cat #: V3211 CAS #: 3684-46-6 Purity ≥ 98%

Description: Broxaldine is an antiprotozoal drug that can also be used in the treatment of leprosy. It was formerly given by mouth, with broxyquinoline, in the treatment of intestinal protozoal infections, including amoebiasis, but less toxic drugs are preferred. It has an InChI of 1S/C17H11Br2NO2/c1-10-7-8-12-13(18)9-14(19)16(15(12)20-10)22-17(21)11-5-3-2-4-6-11/h2-9H,1H3; and InChI KEY of IJTPLVAAROHGGB-UHFFFAOYSA-N; SMILES Code of CC1=NC2=C(C=C1)C(=CC(=C2OC(=O)C3=CC=CC=C3)Br)Br; Chemical/IUPAC name of (5,7-dibromo-2-methylquinolin-8-yl) benzoate.

References: Hazra SK, et al. Therapeutic trial of a combination of broxyquinoline and brobenzoxaldine in the treatment of leprosy. Lepr India. 1979 Oct;51(4):505-10.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	421.08
Molecular Formula	C₁₇H₁₁Br₂NO₂
CAS No.	3684-46-6
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: >10mMr
	Water: N/Ar
	Ethanol: N/A
SMILES Code	CC1=NC2=C(OC(C3=CC=CC=C3)=O)C(Br)=CC(Br)=C2C=C1
Synonyms	Brobenzoxaldine; AL 307; AL-307; AL307

Protocol	In Vitro	In vitro activity: Kinase Assay: Cell Assay:

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.3748 mL	11.8742 mL	23.7485 mL	47.4969 mL
5mM	0.4750 mL	2.3748 mL	4.7497 mL	9.4994 mL
10mM	0.2375 mL	1.1874 mL	2.3748 mL	4.7497 mL
20mM	0.1187 mL	0.5937 mL	1.1874 mL	2.3748 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.