Brivudine
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 2g | $550 | Check With Us |
| 5g | $1050 | Check With Us |
| 10g | $1575 | Check With Us |
: Cat #: V14070 CAS #: 69304-47-8 Purity ≥ 99%
Description: Brivudine (Brivox; Helpin ;Zerpex; BVDU; RP101; bromovinyl-deoxyuridine) is a novel and potent uridine analogue and nucleoside analogue with pro-apoptotic and chemosensitizing activities.
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- Related Biological Data
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| Molecular Weight (MW) | 333.13 |
|---|---|
| Molecular Formula | C11H13BrN2O5 |
| CAS No. | 69304-47-8 |
| Synonyms | RP101. Chemical (E)5(2bromovinyl)2deoxyuridine |
| Protocol | In Vitro | Brivudine is an analogue of thymidine and is incorporated into viral DNA. It blocks the action of DNA polymerase, which inhibits viral replication. It has a stronger antiviral effect against varicella-zoster virus than reference compounds such as acyclovir or penciclovir |
|---|---|---|
| In Vivo | At a dose of 125 mg once daily, Brivudine was superior to acyclovir in reducing the time to produce new blisters and shortening the duration of postherpetic neuralgia |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.0018 mL | 15.0092 mL | 30.0183 mL | 60.0366 mL |
| 5mM | 0.6004 mL | 3.0018 mL | 6.0037 mL | 12.0073 mL |
| 10mM | 0.3002 mL | 1.5009 mL | 3.0018 mL | 6.0037 mL |
| 20mM | 0.1501 mL | 0.7505 mL | 1.5009 mL | 3.0018 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.