BRD4 Inhibitor-24

This product is for research use only, not for human use. We do not sell to patients.

BRD4 Inhibitor-24
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5mg$80To Be Confirmed
10mg$120To Be Confirmed
50mg$360To Be Confirmed
100mg$590To Be Confirmed
email: [email protected]        [email protected]

Cat #: V44622 CAS #: 309951-18-6 Purity ≥ 99%

Description: BRD4 Inhibitor-24 (compound 3U) is a potent BRD4 inhibitor. BRD4 Inhibitor-24 displays anti-tumor activity on MCF7 and K652 cells with IC50 of 33.7 and 45.9 μM respectively (from patent CN107721975A).

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Molecular Weight (MW)262.261
Molecular FormulaC13H14N2O4
CAS No.309951-18-6
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

Note: This product requires protection from light (avoid light exposure) during transportation and storage.

Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.8130 mL19.0650 mL38.1300 mL76.2599 mL
5mM0.7626 mL3.8130 mL7.6260 mL15.2520 mL
10mM0.3813 mL1.9065 mL3.8130 mL7.6260 mL
20mM0.1906 mL0.9532 mL1.9065 mL3.8130 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
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Volume(start)
V1
 
=
 
Concentration(final)
C2
 
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.