BPTES

This product is for research use only, not for human use. We do not sell to patients.

BPTES
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$599In Stock
500mg$1020In Stock
1g$1530In Stock

Cat #: V1897 CAS #: 314045-39-1 Purity ≥ 98%

Description: BPTES is a potent and selective allosteric Glutaminase GLS1 (KGA) inhibitor with IC50 of 0.16 μM.

References: Elgogary A, et al. Combination therapy with BPTES nanoparticles and targets the metabolic heterogeneity of pancreatic cancer. Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):E5328-36.

Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products

Product Promise

Promise
Molecular Weight (MW)524.68
Molecular FormulaC24H24N6O2S3
CAS No.314045-39-1
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 100 mg/mL (190.6 mM)r
Water: <1 mg/mLr
Ethanol: <1 mg/mL
SMILES CodeO=C(NC1=NN=C(CCSCCC2=NN=C(NC(CC3=CC=CC=C3)=O)S2)S1)CC4=CC=CC=C4
SynonymsBPTES
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.9059 mL9.5296 mL19.0592 mL38.1185 mL
5mM0.3812 mL1.9059 mL3.8118 mL7.6237 mL
10mM0.1906 mL0.9530 mL1.9059 mL3.8118 mL
20mM0.0953 mL0.4765 mL0.9530 mL1.9059 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.