Bopindolol Malonate

This product is for research use only, not for human use. We do not sell to patients.

Bopindolol Malonate
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$450To Be Confirmed
1g$750To Be Confirmed
5g$2025To Be Confirmed

Cat #: V13038 CAS #: 82857-38-3 Purity ≥ 99%

Description: Bopindolol Malonate (CTK-8F8315; LS-120081; HE-393689; D-01794) is a potent beta adrenoceptor antagonist with the potential to be used for essential and renovascular hypertension.

References: Harron DW, et al. Bopindolol. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy. Drugs. 1991 Jan;41(1):130-49.

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Product Promise

Promise
Molecular Weight (MW)484.54
Molecular FormulaC26H32N2O7
CAS No.82857-38-3
ProtocolIn VivoBopindolol (intravenous injection; 8, 16 and 32 μg/kg) causes a dose-dependent inhibition of isoprenaline-induced tachycardia, and this agent is 4 times more potent than propranolol in anaesthetised dogs
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.0638 mL10.3191 mL20.6381 mL41.2763 mL
5mM0.4128 mL2.0638 mL4.1276 mL8.2553 mL
10mM0.2064 mL1.0319 mL2.0638 mL4.1276 mL
20mM0.1032 mL0.5160 mL1.0319 mL2.0638 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.