This product is for research use only, not for human use. We do not sell to patients.
| Size | Price | Stock |
|---|---|---|
| 250mg | $1080 | Check With Us |
| 500mg | $1550 | Check With Us |
| 1g | $2325 | Check With Us |
: Cat #: V4930 CAS #: 2280037-51-4 HCl Purity ≥ 98%
Description: Bobcat339 HCl is a novel and potent cytosine-based TET enzyme inhibitor with IC50 of 33 μM (TET1) and 73 μM (TET2).
References: Chua GNL, et al. Cytosine-Based TET Enzyme Inhibitors. ACS Med Chem Lett. 2019 Jan 31;10(2):180-185.
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- Protocol
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| Molecular Weight (MW) | 334.20 |
|---|---|
| Molecular Formula | C16H13Cl2N3O |
| CAS No. | 2280037-51-4 HCl |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| SMILES Code | O=C1N=C(N)C(Cl)=CN1C2=CC(C3=CC=CC=C3)=CC=C2.[H]Cl |
| Synonyms | Bobcat339; Bobcat-339; Bobcat 339; Bobcat339 HCl; Bobcat339 hydrochloride |
| Protocol | In Vitro | Bobcat339 (10 μM; 24 hours) significantly reduces global 5hmC levels by inhibiting TET enzyme function in HT-22 cells. |
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| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.9922 mL | 14.9611 mL | 29.9222 mL | 59.8444 mL |
| 5mM | 0.5984 mL | 2.9922 mL | 5.9844 mL | 11.9689 mL |
| 10mM | 0.2992 mL | 1.4961 mL | 2.9922 mL | 5.9844 mL |
| 20mM | 0.1496 mL | 0.7481 mL | 1.4961 mL | 2.9922 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.