This product is for research use only, not for human use. We do not sell to patients.
| Size | Price | Stock |
|---|---|---|
| 250mg | $1000 | In Stock |
| 500mg | $1550 | In Stock |
| 500mg | $2325 | In Stock |
: Cat #: V4331 CAS #: 2280037-51-4 Purity ≥ 98%
Description: Bobcat339 is a novel and potent cytosine-based TET enzyme inhibitor with IC50 of 33 μM (TET1) and 73 μM (TET2).
References: Chua GNL, et, al. Cytosine-Based TET Enzyme Inhibitors. ACS Med Chem Lett. 2019 Jan 31; 10(2): 180-185.
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| Molecular Weight (MW) | 297.74 |
|---|---|
| Molecular Formula | C16H12ClN3O |
| CAS No. | 2280037-51-4 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| SMILES Code | O=C1N=C(N)C(Cl)=CN1C2=CC(C3=CC=CC=C3)=CC=C2 |
| Synonyms | Bobcat339; Bobcat-339; Bobcat 339; Bobcat339 free base |
| Protocol | In Vitro | Bobcat339 (10 μM; 24 hours) significantly reduces global 5hmC levels by inhibiting TET enzyme function in HT-22 cells. |
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| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.3586 mL | 16.7932 mL | 33.5864 mL | 67.1727 mL |
| 5mM | 0.6717 mL | 3.3586 mL | 6.7173 mL | 13.4345 mL |
| 10mM | 0.3359 mL | 1.6793 mL | 3.3586 mL | 6.7173 mL |
| 20mM | 0.1679 mL | 0.8397 mL | 1.6793 mL | 3.3586 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.