BMX-IN-1

This product is for research use only, not for human use. We do not sell to patients.

BMX-IN-1
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1040Check With Us
250mg$1800Check With Us
500mg$2700Check With Us

Cat #: V4782 CAS #: 1431525-23-3 Purity ≥ 98%

Description: BMX-IN-1 is a novel, potent, selective and covalent / irreversible BMX (bone marrow tyrosine kinase on chromosome X) inhibitor with the potential for treating prostate cancer.

References: Feiyang Liu , et al. Discovery of a Selective Irreversible BMX Inhibitor for Prostate Cancer. ACS Chem. Biol., DOI: 10.1021/cb4000629

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Product Promise

Promise
Molecular Weight (MW)524.59
Molecular FormulaC29H24N4O4S
CAS No.1431525-23-3
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeC=CC(NC1=CC(N2C(C=CC3=C2C4=CC(C5=CC=C(NS(=O)(C)=O)C=C5)=CC=C4N=C3)=O)=CC=C1C)=O
SynonymsBMX-IN-1; BMX-IN1; BMX-IN 1
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.9063 mL9.5313 mL19.0625 mL38.1250 mL
5mM0.3813 mL1.9063 mL3.8125 mL7.6250 mL
10mM0.1906 mL0.9531 mL1.9063 mL3.8125 mL
20mM0.0953 mL0.4766 mL0.9531 mL1.9063 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.