This product is for research use only, not for human use. We do not sell to patients.
| Size | Price | Stock |
|---|---|---|
| 250mg | $1080 | Check With Us |
| 500mg | $1550 | Check With Us |
| 1g | $2325 | Check With Us |
: Cat #: V3470 CAS #: 1257213-50-5 Purity ≥ 98%
Description: BMS-986020 (also known as AM152 and AP-3152 free acid) is a novel, potent and selective LPA1 (lysophosphatidic acid) antagonist.
References: Kihara Y, et al. Lysophospholipid receptors in drug discovery. Exp Cell Res. 2015 May 1;333(2):171-7.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 482.53 |
|---|---|
| Molecular Formula | C29H26N2O5 |
| CAS No. | 1257213-50-5 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent |
| Protocol | In Vitro | BMS-986020 (0.1-10 nM; pre-incubated) concentration-dependent displacement of [18F]BMT-083133 binding is observed in LPA1+ cells and lung sections. At 0.1 nM, the percent displacement in healthy mice, bleomycin mice, and IPF lungs is 18%, 24%, and 31%, respectively. At 10 nM, the percent displacement is 73%, 76%, and 64%, respectively. |
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| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.0724 mL | 10.3621 mL | 20.7241 mL | 41.4482 mL |
| 5mM | 0.4145 mL | 2.0724 mL | 4.1448 mL | 8.2896 mL |
| 10mM | 0.2072 mL | 1.0362 mL | 2.0724 mL | 4.1448 mL |
| 20mM | 0.1036 mL | 0.5181 mL | 1.0362 mL | 2.0724 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.