BMS-983970
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $1980 | Check With Us |
| 250mg | $2980 | Check With Us |
| 500mg | $4470 | Check With Us |
: Cat #: V3478 CAS #: 1584713-87-0 Purity ≥ 98%
Description: BMS-906024 is a novel, oral and potent pan-Notch inhibitor that demonstrated robust anti-tumor activity at tolerated doses in multiple tumor xenograft models.
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| Molecular Weight (MW) | 518.5126 |
|---|---|
| Molecular Formula | C26H26F4N4O3 |
| CAS No. | 1584713-87-0 |
| Storage | -20℃ for 3 years in powder formrr |
| -80℃ for 2 years in solvent | |
| SMILES Code | FC1=C(NC([C@@H](NC([C@H](CCC(F)(F)F)[C@H](CC2CC2)C(N)=O)=O)N=C3C4=CC=CC=C4)=O)C3=CC=C1 |
| Synonyms | BMS-983970; BMS 983970; BMS983970 |
| Protocol | In Vivo | BMS-983970 demonstrates anti-tumor activity in T-cell acute lymphoblastic leukemia (T-ALL) and solid tumor xenograft models |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.9286 mL | 9.6430 mL | 19.2859 mL | 38.5719 mL |
| 5mM | 0.3857 mL | 1.9286 mL | 3.8572 mL | 7.7144 mL |
| 10mM | 0.1929 mL | 0.9643 mL | 1.9286 mL | 3.8572 mL |
| 20mM | 0.0964 mL | 0.4821 mL | 0.9643 mL | 1.9286 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.