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BML-190 (Indomethacin morpholinylamide; IMMA)

This product is for research use only, not for human use. We do not sell to patients.

BML-190 (Indomethacin morpholinylamide; IMMA)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$690Check With Us
1g$1150Check With Us
5g$2990Check With Us

Cat #: V1520 CAS #: 2854-32-2 Purity ≥ 98%

Description: BML-190 (formerly IMMA; LM-4131; BML-190; LM4131; BML190; Indomethacin morpholinylamide), is a potent and selective cannabinoid CB2 receptor inverse agonist with potential anti-inflammatory activity.

References: Klegeris, Andis; Bissonnette, Christopher J.; McGeer, Patrick L. Reduction of human monocytic cell neurotoxicity and cytokine secretion by ligands of the cannabinoid-type CB2 receptor. British Journal of Pharmacology (2003), 139(4), 775-786.

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Product Promise

Promise
Molecular Weight (MW)426.89
Molecular FormulaC23H23ClN2O4
CAS No.2854-32-2
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 22 mg/mL (51.5 mM)r
Water: <1 mg/mLr
Ethanol: <1 mg/mL
SynonymsBML-190; IMMA; LM-4131; BML 190; LM4131; BML190; LM 4131; Indomethacin Morpholinylamide
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.3425 mL11.7126 mL23.4252 mL46.8505 mL
5mM0.4685 mL2.3425 mL4.6850 mL9.3701 mL
10mM0.2343 mL1.1713 mL2.3425 mL4.6850 mL
20mM0.1171 mL0.5856 mL1.1713 mL2.3425 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.