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BioE-1115

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BioE-1115
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Cat #: V0712 CAS #: 1268863-35-9 Purity ≥ 99%

Description: BioE-1115 (BioE 1115) is a novel, potent and highly selective PAS kinase (PASK) inhibitor with an IC50 of ~4 nM, it is also a potent casein kinase 2α inhibitor with an IC50 of ~10 μM. It is a dual inhibitor of PAS kinase (PASK) and casein kinase 2α (CK2α).

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Molecular FormulaC₁₉H₁₈FN₃O₂
CAS No.1268863-35-9
SynonymsBioE-1115; BioE 1115; BioE1115
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.