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Size | Price | Stock |
---|---|---|
10mg | $250 | 3~6 Days |
25mg | $450 | 3~6 Days |
50mg | $800 | 3~6 Days |
100mg | $1350 | 3~6 Days |
Cat #: V41447 CAS #: 1798787-27-5 Purity ≥ 99%
Description: BIIB068 (BIIB-068) is a novel reversible and orally bioavailable BTK inhibitor with the potential to be used for autoimmune diseases such as systemic lupus erythematosus (SLE). It demonstrated good kinome selectivity with good overall drug-like properties for oral dosing, was well tolerated across preclinical species at pharmacologically relevant doses with good ADME properties, and achieved >90% inhibition of BTK phosphorylation (pBTK) in humans.
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Molecular Weight (MW) | 435.532 |
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Molecular Formula | C23H29N7O2 |
CAS No. | 1798787-27-5 |
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 2.2960 mL | 11.4802 mL | 22.9604 mL | 45.9209 mL |
5mM | 0.4592 mL | 2.2960 mL | 4.5921 mL | 9.1842 mL |
10mM | 0.2296 mL | 1.1480 mL | 2.2960 mL | 4.5921 mL |
20mM | 0.1148 mL | 0.5740 mL | 1.1480 mL | 2.2960 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.