BIBF0775
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $850 | Check With Us |
| 250mg | $1450 | Check With Us |
| 500mg | $2175 | Check With Us |
: Cat #: V3313 CAS #: 334951-90-5 Purity ≥ 98%
Description: BIBF0775, a 6-substituted indolinone analog, is a novel, potent and selective inhibitor of transforming growth factor β (TGFβ) type I receptor (Alk5) with an IC50 of 34 nM.
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- Physicochemical and Storage Information
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- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 494.64 |
|---|---|
| Molecular Formula | C31H34N4O2 |
| CAS No. | 334951-90-5 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 10 mMr |
| Water: N/Ar | |
| Ethanol: N/A | |
| SMILES Code | O=C(C1=CC(NC/2=O)=C(C=C1)C2=C(C3=CC=CC=C3)NC4=CC=C(CN5CCCCC5)C=C4)N(CC)C |
| Synonyms | BIBF0775; BIBF-0775; BIBF 0775 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.0217 mL | 10.1084 mL | 20.2167 mL | 40.4334 mL |
| 5mM | 0.4043 mL | 2.0217 mL | 4.0433 mL | 8.0867 mL |
| 10mM | 0.2022 mL | 1.0108 mL | 2.0217 mL | 4.0433 mL |
| 20mM | 0.1011 mL | 0.5054 mL | 1.0108 mL | 2.0217 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
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Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.