BETRIXABAN

This product is for research use only, not for human use. We do not sell to patients.

BETRIXABAN
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5mg$803-6 Days
10mg$1203-6 Days
25mg$1903-6 Days
50mg$3003-6 Days
100mg$4103-6 Days
250mg$6103-6 Days
500mg$8603-6 Days
email: [email protected]        [email protected]

Cat #: V3917 CAS #: 330942-05-7 Purity ≥ 99%

Description: Betrixaban (trade name Bevyxxa; formerly PRT054021; MK-4448; PRT-021; MLN-1021 etc.) is a highly potent, selective, and orally bioavailalbe anticoagulant drug which acts as a direct factor Xa inhibitor. As of 2017, Betrixaban is approved by FDA for venous thrombosis prevention in adults hospitalized for an acute medical illness who are at risk for thromboembolic complications due to restricted mobility and other risk factors. Compared to other DOACs betrixaban has relatively low renal excretion (ca. 17%) and is not metabolized by CYP3A4.

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Molecular Weight (MW)451.91
Molecular FormulaC23H22ClN5O3
CAS No.330942-05-7
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

SynonymsPRT054021; PRT-021; MK-4448; MLN-1021; PRT 054021; PRT-054021; MK4448; MLN 1021; PRT 021; PRT021; MK 4448; MLN1021; trade name Bevyxxa
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.2128 mL11.0641 mL22.1283 mL44.2566 mL
5mM0.4426 mL2.2128 mL4.4257 mL8.8513 mL
10mM0.2213 mL1.1064 mL2.2128 mL4.4257 mL
20mM0.1106 mL0.5532 mL1.1064 mL2.2128 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
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Volume(start)
V1
 
=
 
Concentration(final)
C2
 
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.