Betamethasone (NSC-39470; SCH-4831)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 2g | $200 | Check With Us |
| 5g | $380 | Check With Us |
| 10g | $570 | Check With Us |
: Cat #: V1708 CAS #: 378-44-9 Purity ≥ 98%
Description: Betamethasone (also called NSC-39470; SCH-4831; NSC39470; SCH4831) is a glucocorticoid steroid and an approved medication with moderate anti-inflammatory and immunosuppressive activities.
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- Physicochemical and Storage Information
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- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 392.46 |
|---|---|
| Molecular Formula | C22H29FO5 |
| CAS No. | 378-44-9 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 79 mg/mL (201.3 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 10 mg/mL (25.5 mM) | |
| Synonyms | NSC-39470; SCH-4831; NSC39470; SCH4831; NSC 39470; SCH 4831 |
| Protocol | In Vivo | Betamethasone (0.48 mg; i.v.gtt for 48 h) decreases the hypercapnia-induced increase in CBF due to decreased cerebral vasodilatation |
|---|---|---|
| Animal model | Rambouillet-Colombia ewes bred on a single occasion are received hypercapnic challenges | |
| Dosages | 0.48 mg | |
| Administration | Injected into the fetal jugular vein at a rate of 1 ml/h (10 μg betamethasone/h) and maintained over the next 48 h. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.5480 mL | 12.7402 mL | 25.4803 mL | 50.9606 mL |
| 5mM | 0.5096 mL | 2.5480 mL | 5.0961 mL | 10.1921 mL |
| 10mM | 0.2548 mL | 1.2740 mL | 2.5480 mL | 5.0961 mL |
| 20mM | 0.1274 mL | 0.6370 mL | 1.2740 mL | 2.5480 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.