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Bendazac

This product is for research use only, not for human use. We do not sell to patients.

Bendazac
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5g$180Check With Us
10g$250Check With Us
20g$375Check With Us

Cat #: V12381 CAS #: 20187-55-7 Purity ≥ 98%

Description: Bendazac (trade name Nevanac among others) is a NSAID (nonsteroidal anti-inflammatory drug) approved for use as a prescription eye drop 0.1% solution or 0.3% solution.

References: Balfour JA, et al. Bendazac lysine. A review of its pharmacological properties and therapeutic potential in the management of cataracts. Drugs. 1990;39(4):575-596.

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Molecular Weight (MW)282.29
Molecular FormulaC16H14N2O3
CAS No.20187-55-7
SMILES CodeO=C(O)COC1=NN(CC2=CC=CC=C2)C3=C1C=CC=C3
SynonymsBendazac; AF 983; AF-983; AF983; Bendazolic acid; Bindazac; Versus
ProtocolIn VitroBendazac is an anti-inflammatory agent endowed with protein antidenaturant properties effective for various inflammatory skin conditions. Bendazac has been shown to be a strong reacting substrate in a chemical oxidizing system, which mimics a physiological pathway of hydroxy radical generation.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.5425 mL17.7123 mL35.4246 mL70.8491 mL
5mM0.7085 mL3.5425 mL7.0849 mL14.1698 mL
10mM0.3542 mL1.7712 mL3.5425 mL7.0849 mL
20mM0.1771 mL0.8856 mL1.7712 mL3.5425 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.