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 BC-DXI-843

This product is for research use only, not for human use. We do not sell to patients.

 BC-DXI-843
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5mg$1353-6 Days
10mg$2003-6 Days
25mg$3503-6 Days
50mg$5503-6 Days
100mg$9503-6 Days
250mg$14503-6 Days
500mg$21503-6 Days
email: [email protected]        [email protected]

Cat #: V2167 CAS #: 2421117-98-6 Purity ≥ 98%

Description: BC-DXI-843 is a potent and specific AIMP2-DX2 inhibitor with an IC50 of 0.92 μM, more than 100-fold selectivity over AIMP2 (IC50 >100 μM) in a luciferase assay. BC-DXI-843 acts as a promising lead targeting AIMP2-DX2 in lung cancer.

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Molecular Weight (MW)546.66
CAS No.2421117-98-6
SMILES Code O=C(NC1=NC(C2=CC=C(OC)C=C2)=CS1)[C@@H](NS(=O)(C3=CC=C(C)C=C3)=O)CC4=CNC5=C4C=CC=C5
Synonyms BCDXI843; BCDXI-843; BCDXI 843; BC-DXI-843; BC-DXI843; BC-DXI 843
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.8293 mL9.1465 mL18.2929 mL36.5858 mL
5mM0.3659 mL1.8293 mL3.6586 mL7.3172 mL
10mM0.1829 mL0.9146 mL1.8293 mL3.6586 mL
20mM0.0915 mL0.4573 mL0.9146 mL1.8293 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
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Concentration
 
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Volume
 
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.