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BAY-474

This product is for research use only, not for human use. We do not sell to patients.

BAY-474
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1200Check With Us
200mg$1800Check With Us
500mg$3040Check With Us
email: [email protected]        [email protected]

Cat #: V40400 CAS #: 1033767-86-0 Purity ≥ 99%

Description: BAY-474 is a novel and potent inhibitor of tyrosine-protein kinase c-Met, acting as a structural genomics consortium (SGC) epigenetics probe.

References: Müller S, et al. Donated chemical probes for open science. Elife. 2018 Apr 20;7. pii: e34311.

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Molecular Weight (MW)289.33
Molecular FormulaC17H15N5
CAS No.1033767-86-0
SMILES CodeN#CC1=C(C)NC(C)=C(C#N)C1C2=CC3=C(NN=C3C)C=C2
SynonymsBAY-474; BAY474; BAY 474
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.4563 mL17.2813 mL34.5626 mL69.1252 mL
5mM0.6913 mL3.4563 mL6.9125 mL13.8250 mL
10mM0.3456 mL1.7281 mL3.4563 mL6.9125 mL
20mM0.1728 mL0.8641 mL1.7281 mL3.4563 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.