BAY-1125976

This product is for research use only, not for human use. We do not sell to patients.

BAY-1125976
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1020Check With Us
500mg$1680Check With Us
1g$2520Check With Us

Cat #: V4127 CAS #: 1402608-02-9 Purity ≥ 98%

Description: BAY1125976 (BAY-1125976) is a novel, orally bioavailable and selective allosteric inhibitor of Akt1/Akt2 with potential anticancer activity.

References: Politz O, et al. BAY 1125976, a selective allosteric AKT1/2 inhibitor, exhibits high efficacy on AKT signaling-dependent tumor growth in mouse models. Int J Cancer. 2017 Jan 15;140(2):449-459.

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Product Promise

Promise
Molecular Weight (MW)383.45
Molecular FormulaC23H21N5O
CAS No.1402608-02-9
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeO=C(C1=NN2C(C=C1)=NC(C3=CC=C(C4(N)CCC4)C=C3)=C2C5=CC=CC=C5)N
SynonymsBAY-1125976; BAY 1125976; BAY1125976;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.6079 mL13.0395 mL26.0790 mL52.1580 mL
5mM0.5216 mL2.6079 mL5.2158 mL10.4316 mL
10mM0.2608 mL1.3040 mL2.6079 mL5.2158 mL
20mM0.1304 mL0.6520 mL1.3040 mL2.6079 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.