Bavisant dihydrochloride hydrate

This product is for research use only, not for human use. We do not sell to patients.

Bavisant dihydrochloride hydrate
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5mg$1403-6 Days
10mg$2303-6 Days
25mg$3903-6 Days
50mg$6003-6 Days
100mg$8403-6 Days
250mg$12303-6 Days
500mg$17403-6 Days
email: [email protected]        [email protected]

Cat #: V4516 CAS #: 1103522-80-0 Purity ≥ 99%

Description: Bavisant dihydrochloride hydrate (also known as JNJ-31001074 dihydrochloride hydrate) is a novel, highly selective, orally bioactive antagonist of the human H3 receptor with a novel mechanism of action which involves wakefulness and cognition. It might be applied as an ADHD treatment. Non-histamine neurons contain histamine H3 receptors, which control other neurotransmitters like acetylcholine and norepinephrine. This suggests that H3 antagonists may be able to reduce impulsivity and enhance attention. According to research, H3 receptor antagonists may have a special therapeutic effect and provide a significant alternative for the treatment of ADHD because of their novel mechanism of action.

Top Publications Citing Invivochem Products
Product Catalog 2022
Bulletin Board
Guide to Product Handling
Publications Citing InvivoChem Products
Product Promise
Promise
Molecular Weight (MW)420.37374329567
Molecular FormulaC19H31Cl2N3O3
CAS No.1103522-80-0
Storage

Powder      -20°C    3 years

                     4°C     2 years

In solvent   -80°C    6 months

                  -20°C    1 month

Note: Please store this product in a sealed and protected environment, avoid exposure to moisture.

SynonymsBavisant dihydrochloride hydrate; JNJ-31001074-AAC; JNJ 31001074-AAC; JNJ31001074-AAC
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.3788 mL11.8942 mL23.7884 mL47.5767 mL
5mM0.4758 mL2.3788 mL4.7577 mL9.5153 mL
10mM0.2379 mL1.1894 mL2.3788 mL4.7577 mL
20mM0.1189 mL0.5947 mL1.1894 mL2.3788 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
=
Concentration
 
×
Volume
 
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
×
 
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.