Basifungin | CAS 127785-64-2

Basifungin

This product is for research use only, not for human use. We do not sell to patients.

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Size	Price	Stock
100mg	$2500	Check With Us
200mg	$3750	Check With Us
500mg	$6300	Check With Us

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Cat #: V5560 CAS #: 127785-64-2 Purity ≥ 98%

Description: Basifungin is an inositol phosphorylceramide synthase inhibitor that is extracted from the culture medium of Aureobasidium pullulans R 106.

References: K Ikai, et al. Structure of aureobasidin A. J Antibiot (Tokyo). 1991 Sep;44(9):925-33.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	1101.42
Molecular Formula	C60H92N8O11
CAS No.	127785-64-2
SMILES Code	CC(C)(O)[C@@]1(C(O1)=O)N(C([C@H](CC(C)C)NC([C@H](C(C)C)N(C([C@H]([C@H](C)CC)NC([C@H]2N(C([C@H](CC3=CC=CC=C3)N(C([C@H](CC4=CC=CC=C4)NC([C@H](C(C)C)N(C(C(O)C(C)CC)=O)C)=O)=O)C)=O)CCC2)=O)=O)C)=O)=O)C
Synonyms	Basifungin; Aureobasidin A; NK 204 R106-1; LY 295337; LY295337;

Protocol	In Vitro	Aureobasidin A arrests growth of yeast cells through both ceramide intoxication and deprivation of essential inositolphosphorylceramides.

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	0.9079 mL	4.5396 mL	9.0792 mL	18.1584 mL
5mM	0.1816 mL	0.9079 mL	1.8158 mL	3.6317 mL
10mM	0.0908 mL	0.4540 mL	0.9079 mL	1.8158 mL
20mM	0.0454 mL	0.2270 mL	0.4540 mL	0.9079 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.

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