BAPTA Tetrasodium

This product is for research use only, not for human use. We do not sell to patients.

BAPTA Tetrasodium
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1g$150Check With Us
5g$450Check With Us
10g$675Check With Us

Cat #: V6123 CAS #: 126824-24-6 Purity ≥ 98%

Description: BAPTA, an intercellular and selective fluorescent Ca2+ chelator, is a novel and potent neuroprotective agent usef for cerebral ischemia.

References: R Y Tsien, et al. New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures. Biochemistry. 1980 May 27;19(11):2396-404. 

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Molecular Weight (MW)564.36
Molecular FormulaC22H20N2Na4O10
CAS No.126824-24-6
SMILES CodeO=C(O[Na])CN(CC(O[Na])=O)C1=CC=CC=C1OCCOC2=CC=CC=C2N(CC(O[Na])=O)CC(O[Na])=O
SynonymsBAPTA-Na4; BAPTA Na4; BAPTANa4; BAPTA Tetrasodium
ProtocolIn VitroBAPTA (0.3-30 μM; 1 h) can be used for the prevention of [Ca2+]-induced cell damage, but disturbe calcium signalling in isingle differentiated NH15-CA2 neuroblastoma and glioma hybrid cells.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.7719 mL8.8596 mL17.7192 mL35.4384 mL
5mM0.3544 mL1.7719 mL3.5438 mL7.0877 mL
10mM0.1772 mL0.8860 mL1.7719 mL3.5438 mL
20mM0.0886 mL0.4430 mL0.8860 mL1.7719 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.